This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.
More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Phospho-PDE5A Antibody Species Reactivity Human, Mouse Published species Human, Insect, Mouse Host/Isotype Rabbit / IgG Class Recombinant Monoclonal Type Antibody Clone D12H7L17 Immunogen A...
Testosterone Polyclonal Antibody Species Reactivity Chemical Host/Isotype Sheep / IgG Class Polyclonal Type Antibody Immunogen 17b-Testosterone(7)-BTG Conjugate Unconjugated Form Liquid...
Polyclonal Antibody to Glyci. Product No. PAS117Ge01 Organism Species Pan-species (General) Same name, Different species. Source Polyclonal antibody preparation Host Rabbit Ig Type IgG...