Rabbit Anti-Dengue Virus Type 4
Concentration ≥ 2 mg/mL by OD280 nm
Storage Buffer D-PBS, pH 7.2-7.4
Preservatives 0.099% NaN3
Purity ≥ 95% on 12.5% SDS-PAGE
Purification Antigen-affinity chromatography
Application Coating or conjugate antibody in ELISA, ICT. Paring with B7050, B7051 or other NS1 antibodies Cross Reactivity Reactive with Zika virus NS1
Dengue virus (DENV) is a single positive strand RNA virus of the Flaviviridae family and a causative agent of the infectious tropical disease Dengue fever. There are four serotypes of the virus, DENV-1, DENV-2, DENV-3 and DENV-4. Dengue NS1 (Non-Structural protein 1) is a versatile glycoprotein of the DENV that is secreted as a hexamer, binds to the cell surface, and has immune evasive functions.
Dengue NS1 antigen is also used as an early detection marker (days 1 to 9 after onset) for dengue virus infection.
B7060 was generated against recombinant DENV-2 NS1 protein expressed from insect cells and purified from rabbit serum via antigen-affinity chromatography. It recognizes NS1s of all 4 types of dengue viruses.